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Pet Health Library

Dogs + Medications & Supplements

  • Cyclosporine is given by mouth and is used to treat atopic dermatitis in dogs and cats. It has also been used off-label to treat other types of immune-mediated conditions. Give as directed. The most common side effects include stomach upset, such as vomiting, diarrhea, and decreased appetite. Do not use in pets with severe infections, a history of cancer, allergies to the medication, that are nursing or pregnant, or in pets younger than six months old. If a negative reaction occurs, contact your veterinarian.

  • Cyproheptadine is given by mouth and is used off label to treat allergic skin conditions, certain toxicities, and to stimulate appetite. Give as directed by your veterinarian. Common side effects include sleepiness, increased appetite, and dry mouth. Do not use in pets that are allergic to it or pets undergoing skin allergy testing within the next two weeks. If a negative reaction occurs, please call your veterinary office.

  • Cytarabine is a chemotherapy medication commonly used off label to treat blood cancers and brain inflammation. It is an injectable solution usually given in the vein by a veterinary professional. Common side effects include gastrointestinal upset and low blood cell counts. This medication should not be used or used with caution in pets with liver or kidney disease, those that have an allergy to this medication, and pregnant/lactating pets. If a negative reaction occurs, call your veterinary office.

  • Decoquinate is given by mouth and is used off label in dogs to prevent coccidia infections. Side effects are uncommon. Do not use in animals that are allergic to it or to treat coccidia infections (only use as a preventive).

  • Deracoxib (brand name Deramaxx) is a non-steroidal anti-inflammatory drug (NSAID) used in dogs after surgery to reduce the pain associated with surgery (e.g., orthopedic and dental surgeries), as well as for the treatment of osteoarthritis. This article discusses possible side effects, risk factors, drug interactions, monitoring, and proper storage.

  • Desmopressin is administered into the eye or is given as an injection and is used off label to treat diabetes insipidus and von Willebrand disease. Give as directed by your veterinarian. Side effects are uncommon but may include irritation upon application to the eye. Do not use in pets that are allergic to it or pets that are prone to blood clots, such as those with heart disease. If a negative reaction occurs, please call your veterinary office.

  • Desoxycorticosterone pivalate (DOCP) (brand name Percorten-V®, Zycortal®) is a steroid hormone replacement therapy used to treat primary hypoadrenocorticism (Addison’s disease) in dogs. Extra-label (off-label) lower dosages of DOCP (i.e., lower dose, longer dosing interval, or both) can be used to control the balance of blood electrolyte levels. DOCP has also been used extra-label to treat hypoadrenocorticism in cats.

  • Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea. Do not use in pets that are allergic to it, have systemic fungal infections, diabetes, or stomach or intestinal ulcers, or are taking NSAIDs. It should not be used in rabbits or in surgical pets. If a negative reaction occurs, please call your veterinary office.

  • Dexamethasone ophthalmic is a topical steroid medication used to treat inflammatory eye conditions in cats, dogs, rabbits, avian species, and other animals. Dexamethasone ophthalmic may be used alone or in combination with an antimicrobial. Dexamethasone ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulcerations or corneal infections.

  • Dexamethasone Otic is a steroid medication used in pets to treat topical inflammation of the ears, often with other medications such as antibiotics. It comes as a liquid solution that is prescribed for topical use within a pet’s ear canal. There are no veterinary brands of dexamethasone otic.