Pet Health Library
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Xanthine bladder stones are an uncommon type of urinary stone that can occur in both dogs and cats. Xanthine is produced when purines (a component of animal proteins) are broken down within the body. Most dogs can further break down xanthine into other substances that are easily excreted, but some dogs are deficient in an enzyme that is required for this breakdown to occur. These dogs develop elevated levels of xanthine in the urine, resulting in xanthine stones forming within the urinary tract. They can also form secondary to administration of a medication called Allopurinol. Xanthine urinary tract stones are typically removed surgically. Affected dogs require long-term care with specialized diets to prevent recurrence.